https://doi.org/10.4081/monaldi.2024.2852
Tailored treatment for tuberculosis in transgender individuals: a call for a patient-centered approach from a large Italian cohort
Published: January 11, 2024
Abstract Views: 358
PDF_EARLY VIEW: 223
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Tuberculosis (TB) diagnosis and management in special populations remain challenging. Data about TB and transgender individuals is scarce, and strategies aimed at reducing the TB burden in this at-risk group are needed. We conducted an observational monocentric study from a national reference center for TB, including transgender individuals with active TB in a low-TB burden country (Italy), over 34 years (1990-2023). Sixty-six transgender males and two transgender females (median age 30 years, interquartile range 26-38 years, 65 migrants) were included. Most patients (38/66, 57.6%) lived in poor social conditions. 65.2% (43/66) of patients were people living with HIV. Multidrug- and rifampicin-resistant tuberculosis and isoniazid-resistant TB were diagnosed in five (7.6%) and three (4.5%) patients, respectively. The overall treatment success rate was 72.7% (48/66 patients), with differences observed according to social conditions. Our study highlights the need for a tailored approach to increase treatment success in this at-risk population.
World Health Organization. Global tuberculosis report 2022. Available from: https://iris.who.int/bitstream/handle/10665/363752/9789240061729-eng.pdf?sequence=1.
Matucci T, Riccardi N, Occhineri S, et al. Treatment of latent tuberculosis infection in incarcerated people: a systematic review. Clin Microbiol Infect 2023;29:714-21.
DOI: https://doi.org/10.1016/j.cmi.2023.02.016
Riccardi N, Antonello RM, Ferrarese M, et al. Tuberculosis in migrants: epidemiology, resistance and outcome in Milan, Italy. Infect Dis 2023;55:543-50.
DOI: https://doi.org/10.1080/23744235.2023.2217912
Shah SA, Qayyum S, Baig S, et al. Results of community-based TB and HIV screening among transgender women and male sex workers in Pakistan. PLOS Glob Public Health 2023;3:e0000913.
DOI: https://doi.org/10.1371/journal.pgph.0000913
Pareek M, Greenaway C, Noori T, et al. The impact of migration on tuberculosis epidemiology and control in high-income countries: a review. BMC Med 2016;14:48.
DOI: https://doi.org/10.1186/s12916-016-0595-5
Commission of the European Communities. Commission decision of 28 April 2008 amending decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under decision no 2119/98/EC of the European Parliament and of the Council. In: Official Journal, L159/46, 18/06/2008.
Getahun H, Matteelli A, Chaisson RE, Raviglione M. Latent mycobacterium tuberculosis infection. N Engl J Med 2015;372:2127-35.
DOI: https://doi.org/10.1056/NEJMra1405427
World Health Organization. WHO consolidated guidelines on tuberculosis. Module 4: treatment - drug-resistant tuberculosis treatment, 2022 update. Available from: https://iris.who.int/bitstream/handle/10665/365308/9789240063129-eng.pdf?sequence=1.
Canetti D, Antonello RM, Saderi L, et al. Impact of SARS-CoV-2 infection on tuberculosis outcome and follow-up in Italy during the first COVID-19 pandemic wave: a nationwide online survey. Infez Med 2022;30:418-26.
DOI: https://doi.org/10.53854/liim-3003-10
Morrison H, Perrin F, Dedicoat M, et al. Impact of COVID-19 on NHS tuberculosis services: Results of a UK-wide survey. J Infect 2023;87:59-61.
DOI: https://doi.org/10.1016/j.jinf.2023.04.004
Ethics Approval
The study received ethical approval n. 578–112,018 from the ethical committee of ASST Niguarda Ca′ Granda in Milan (Italy) and it was conducted in agreement with the Declaration of Helsinki (1964) and its later amendments.How to Cite
Riccardi, Niccolò, Roberta Maria Antonello, Maurizio Ferrarese, Alice Repossi, Laura Saderi, Giovanni Fumagalli, Giorgio Besozzi, Giovanni Sotgiu, and Luigi Codecasa. 2024. “Tailored Treatment for Tuberculosis in Transgender Individuals: A Call for a Patient-Centered Approach from a Large Italian Cohort”. Monaldi Archives for Chest Disease, January. https://doi.org/10.4081/monaldi.2024.2852.
Copyright (c) 2024 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Vinnie Sarah Ch Sangma, Surabhi Jaggi, Varinder Saini, Deepak Aggarwal, Pankaj Kumar, Jagdish Chander, Prevalence of latent tuberculosis infection in household contacts of pulmonary tuberculosis, time to treat , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Taymmia Ejaz, Mahmood Iqbal Malik, Jamal Ahmed, Rizwan Azam, Yousaf Jamal, Sheema Saadia, Clinico-radiological and bronchoscopic predictors of microbiological yield in sputum negative tuberculosis in Pakistan , Monaldi Archives for Chest Disease: Vol. 92 No. 3 (2022)
- Vivek Sharma, Pruthu Thekkur, Poonam R. Naik, Brojo Kishore Saha, Niraj Agrawal, Milan K. Dinda, S. Parthiban, Abhijit Dey, Basavaraj Poojar, Amrita N. Shamanewadi, Srinath Satyanarayana, Treatment success rates among tuberculosis patients notified from the private sector in West Bengal, India , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Alexandru Stoichita, Andreea Dumitrescu, Ana Ciobanu, Cristian Oancea, Fildan Petronela, Radu Dabja, Kostyantyn Dumchev, Andrei Dadu, Beatrice Mahler-Boca, Kristina Akopyan, Depression and anxiety symptoms among people with rifampicin-resistant tuberculosis receiving in-patient care in the National Pulmonology Reference Institute in Romania , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Natalia Adamashvili, Kristina Akopyan, Nestani Tukvadze, Kostyantyn Dumchev, Yuliia Sereda, Irma Khonelidze, Giorgi Kuchukhidze, Factors associated with loss to follow-up among people with tuberculosis in the country of Georgia: a cohort study , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- P.L. Migliorati, E. Boccoli, L.S. Bracci, P. Sestini, A.S. Melani, A survey on hospitalised communityacquired pneumonia in Italy , Monaldi Archives for Chest Disease: Vol. 65 No. 2 (2006): Pulmonary series
- B. Chakrabarti, P.D.O. Davies, Pleural tuberculosis , Monaldi Archives for Chest Disease: Vol. 65 No. 1 (2006): Pulmonary series
- Raffaele Griffo, Marco Ambrosetti, Giuseppe Furgi, Roberto Carlon, Carmine Chieffo, Giuseppe Favretto, Oreste Febo, Ugo Corrà , Francesco Fattirolli, Pantaleo Giannuzzi, Cesare Greco, Massimo F. Piepoli, Pier Luigi Temporelli, Roberto Tramarin, Stefano Urbinati, Standards and outcome measures in Cardiovascular Rehabilitation. Position Paper GICR/IACPR , Monaldi Archives for Chest Disease: Vol. 78 No. 4 (2012): Cardiac series
- Seyed Kianoosh Hosseini, Abbas Soleimani, Abbas Ali Karimi, Saeed Sadeghian, Sirous Darabian, Seyed Hesameddin Abbasi, Seyed Hossein Ahmadi, Arezou Zoroufian, Mehran Mahmoodian, Ali Abbasi, Clinical features, management and in-hospital outcome of ST elevation myocardial infarction (STEMI) in young adults under 40 years of age , Monaldi Archives for Chest Disease: Vol. 72 No. 2 (2009): Cardiac series
- J.L. Lopez-Campos, C. Garcia Polo, A. Leon Jimenez, A. Arnedillo, E. Gonzalez-Moya, J.J. Fenandez Berni, Staff training influence on non-invasive ventilation outcome for acute hypercapnic respiratory failure , Monaldi Archives for Chest Disease: Vol. 65 No. 3 (2006): Pulmonary series
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
