https://doi.org/10.4081/monaldi.2024.2855
Existence and pattern of sleep-related breathing disorders in patients diagnosed with bronchial asthma
Submitted: November 25, 2023
Accepted: March 4, 2024
Published: April 23, 2024
Accepted: March 4, 2024
Abstract Views: 303
PDF_EARLY VIEW: 166
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Asthma and obstructive sleep apnea (OSA) are commonly prevalent diseases, and both can co-exist to result in an alternate overlap syndrome, where a bidirectional relationship can adversely affect each other. This study aimed to determine the existence and pattern of sleep-related breathing disorders in subjects with bronchial asthma. It was prospectively conducted at the National Institute of Tuberculosis and Respiratory Diseases, New Delhi, in diagnosed cases of bronchial asthma. A subjective assessment of sleepiness was done using the Epworth sleepiness scale (ESS). All subjects underwent overnight polysomnography (PSG) in the Sleep Laboratory of the Institute. A total of 70 subjects were screened, and among them, finally, 30 were enrolled. The mean age of the subjects was 37.53±11.21 years, the mean body mass index (BMI) was 26.4±5.58 kg/m2, the mean ESS score was 3.1, and 80% of the subjects were male. After PSG, OSA (apnea hypopnea index >5/hour) was found in 63% (19/30) of the patients, of whom 43% had mild OSA, 10% had moderate OSA, and 10% had severe OSA. 10% (3/30) had nocturnal oxygen desaturation, while none had sleep hypoventilation. Patients with OSA compared to those without OSA had a higher BMI, more co-morbid allergic rhinitis, severe bronchial asthma, and a worse percentage of predicted forced expiratory volume in the first second. The study showed high detection rates of OSA in bronchial asthma patients. Hence, asthma patients should be evaluated for OSA.
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Ethics Approval
The study protocol was approved by the Ethical Review Committee of the National Institute of Tuberculosis and Respiratory Diseases (protocol no. 6625 dated 2018/09/29)How to Cite
Meena, Saroj Kumari, Rajnish Gupta, and Manmohan Puri. 2024. “Existence and Pattern of Sleep-Related Breathing Disorders in Patients Diagnosed With Bronchial Asthma”. Monaldi Archives for Chest Disease, April. https://doi.org/10.4081/monaldi.2024.2855.
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