https://doi.org/10.4081/monaldi.2024.2991
Hematological and clinical profiling of chronic obstructive pulmonary disease: a comprehensive study
Submitted: March 14, 2024
Accepted: August 9, 2024
Published: September 30, 2024
Accepted: August 9, 2024
Abstract Views: 223
PDF_EARLY VIEW: 75
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Chronic obstructive pulmonary disease (COPD) presents as a multifaceted clinical landscape with various hematological manifestations. Among these, polycythemia and anemia pose distinct challenges. While the prevalence of polycythemia has decreased in recent years, anemia remains a prevalent concern, impacting patient outcomes. This study investigated the incidence and clinical characteristics of polycythemia in COPD patients, focusing on a diverse cohort in India. Methodological approaches included comprehensive evaluations of clinical parameters, pulmonary function, and hematological profiles. Results revealed significant variations in COPD severity, pulmonary function, and respiratory symptoms among patients with different hemoglobin levels. The findings shed light on the complex interplay between hematological variations and clinical manifestations in COPD, providing valuable insights for disease management strategies.
Agustí A, Celli BR, Criner GJ, et al. Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary. Am J Respirat Crit Care Med 2023;207:819-37.
DOI: https://doi.org/10.1164/rccm.202301-0106PP
Vlahakos V, Marathias K, Lionaki S, et al. The paradigm shift from polycythemia to anemia in COPD: the critical role of the renin–angiotensin system inhibitors. Expert Rev Respir Med 2022;16:391-8.
DOI: https://doi.org/10.1080/17476348.2022.2045958
Kollert F, Tippelt A, Müller C, et al. Hemoglobin levels above anemia thresholds are maximally predictive for long-term survival in COPD with chronic respiratory failure. Respir Care 2013;58:1204-12.
DOI: https://doi.org/10.4187/respcare.01961
Shujaat A, Minkin R, Eden E. Pulmonary hypertension and chronic cor pulmonale in COPD. Int J Chron Obstruct Pulmon Dis 2007;2:273-82.
Chambellan A, Chailleux E, Similowski T. Prognostic value of the hematocrit in patients with severe COPD receiving long-term oxygen therapy. Chest 2005;128:1201-8.
DOI: https://doi.org/10.1378/chest.128.3.1201
Alkhedaide AQ. Tobacco smoking causes secondary polycythemia and a mild leukocytosis among heavy smokers in Taif City in Saudi Arabia. Saudi J Biol Sci 2020;27:407-11.
DOI: https://doi.org/10.1016/j.sjbs.2019.11.001
McMullin M, Harrison C, Ali S, et al. A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline. Br J Haematol 2018;184:176-91.
DOI: https://doi.org/10.1111/bjh.15648
Rimal S, Das SK, Basnet A, et al. Prevalence and clinical impact of anemia in patients diagnosed with chronic obstructive pulmonary disease: a cross‐sectional study. Health Sci Rep 2023;6:e1371.
DOI: https://doi.org/10.1002/hsr2.1371
Balasubramanian A, Henderson RJ, Putcha N, et al. Haemoglobin as a biomarker for clinical outcomes in chronic obstructive pulmonary disease. ERJ Open Res 2021;7:00068-2021.
DOI: https://doi.org/10.1183/23120541.00068-2021
Ganesh M S, Satheesh S, Aravindhan S. Insights into the pathophysiology and therapeutic targets of consequences induced by polycythemia in COPD. Biotech Res Asia 2023;20.
DOI: https://doi.org/10.13005/bbra/3170
Zielinski J, Tobiasz M, Hawrylkiewicz I, et al. Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients: a 6-year prospective study. Chest 1998;113:65-70.
DOI: https://doi.org/10.1378/chest.113.1.65
Zhang J, DeMeo DL, Silverman EK, et al. Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors. BMC Pulm Med 2021;21:235.
DOI: https://doi.org/10.1186/s12890-021-01585-5
Masa JF, Pépin JL, Borel JC, et al. Obesity hypoventilation syndrome. Eur Respir Rev 2019;28:180097.
DOI: https://doi.org/10.1183/16000617.0097-2018
Semenza GL. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology 2009;24:97-106.
DOI: https://doi.org/10.1152/physiol.00045.2008
Pahal P, Hashmi MF, Sharma S. Chronic obstructive pulmonary disease compensatory measures. Treasure Island, FL, USA: StatPearls Publishing; 2024.
Sarkar M, Rajta PN, Khatana J. Anemia in chronic obstructive pulmonary disease: prevalence, pathogenesis, and potential impact. Lung India 2015;32:142-51.
DOI: https://doi.org/10.4103/0970-2113.152626
Kayrak M, Acar K, Gul EE, et al. Electrocardiographic findings in patients with polycythemia vera. Int J Med Sci 2012;9:93-102.
DOI: https://doi.org/10.7150/ijms.9.93
Ethics Approval
This study was approved by Institute Ethics Committee. All the patients were recruited in the study only after obtaining proper consent from the patients or their representatives (NITRD/PGEC/2019/5172).How to Cite
Sharma, Amit, Deepak Rathi, Prerna Jain, and Devika Tayal. 2024. “Hematological and Clinical Profiling of Chronic Obstructive Pulmonary Disease: A Comprehensive Study”. Monaldi Archives for Chest Disease, September. https://doi.org/10.4081/monaldi.2024.2991.
Copyright (c) 2024 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- R. Carbone, A. Douroukas, V. Arena, D. Cantalupi, E. Balleari, R. Ghio, E. Pelosi, Does 18F-fluorodeoxyglucose PET/CT have a role in the management of pulmonary and extra pulmonary sarcoidosis? , Monaldi Archives for Chest Disease: Vol. 69 No. 2 (2008): Pulmonary series
- Rahul Tyagi, Saurabh Mittal, Karan Madan, Ravindra Mohan Pandey, Anjali Pandey, Anant Mohan, Vijay Hadda, Pawan Tiwari, Randeep Guleria, Association of air pollution and COVID-19 in India , Monaldi Archives for Chest Disease: Vol. 94 No. 2 (2024)
- Zeynep Çınar, Eda Macit Aydın, Nurgul Naurzvai, Ayshan Mammadova, Sümeyye Kodalak, Aygül Abbasova, Gül Gürsel, Impact of neurological problems on mechanical ventilation and intensive care unit outcomes in pulmonary intensive care unit patients: a retrospective analysis of a single-center cohort , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Syed Muhammad Zubair, Muhammad Waleed Chaudhry, Ali Bin Sarwar Zubairi, Talha Shahzad, Aqusa Zahid, Ibrahim Ali Khan, Javaid Ahmed Khan, Muhammad Irfan, The effect of ivermectin on non-severe and severe COVID-19 disease and gender-based difference of its effectiveness , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Syed Muhammad Zubair, Mariyam Gohar Ali, Muhammad Irfan, Post tuberculosis radiological sequelae in patients treated for pulmonary and pleural tuberculosis at a tertiary center in Pakistan , Monaldi Archives for Chest Disease: Vol. 92 No. 1 (2022)
- Amarendra Kumar Shukla, Amrutha Peter, Jitendra Kishore Bhargava, Veerendra Arya, Manish Kumar Gupta, Nishtha Yadav, Pawan Tiwari, Sarcoidosis presenting as bilateral optic neuritis after ChAdOx1 nCoV-19 vaccination , Monaldi Archives for Chest Disease: Vol. 93 No. 1 (2023)
- Mamta Singh, Kunal Deokar, Bibhuti Prassan Sinha, Jinish Doshi, CDS Katoch, Infective pulmonary diseases and the eye: a narrative review , Monaldi Archives for Chest Disease: Early Access
- Karina Vieira da Costa, Iara Tainá Cordeiro de Souza, João Victor dos Santos Felix, Celso Brendo Furtado Brandão, Vanessa Michelle de Souza Fernandes, Andressa Bomfim Lugon Favero, Maria Lucrécia de Aquino Gouveia, Dyego Tavares de Lima, José Heriston de Morais Lima, Rafaela Pedrosa, Tatiana Onofre, Geraldo Eduardo Guedes de Brito, Eduardo Eriko Tenorio de França, Efficacy of a rehabilitation protocol on pulmonary and respiratory muscle function and ultrasound evaluation of diaphragm and quadriceps femoris in patients with post-COVID-19 syndrome: a series of cases , Monaldi Archives for Chest Disease: Vol. 93 No. 1 (2023)
- Seyed Hamid Borsi, Seyed Ali Asghar Fakhr Mousavi Fakhr Mousavi, Mehrdad Dargahi Mal-Amir, Heshmatollah Tavakol, Hanieh Raji, Evaluation of the effectiveness of Tadalafil on improving pulmonary function and asthma severity in severe asthmatic patients: a randomized controlled trial study , Monaldi Archives for Chest Disease: Early Access
- Irene Landi, Suliman Alharbil, Abdullah Alfehaid, Sarah Aldosari, Abdalla Eltayeb A.A, Nadiah Alruwaili, Roberto Troisi, Domenico Galzerano, Mario Pirisi, Olga Vriz, Clinical and echocardiographic predictors of outcome in liver transplant patients , Monaldi Archives for Chest Disease: Early Access
<< < 17 18 19 20 21 22 23 24 25 26 > >>
You may also start an advanced similarity search for this article.
