https://doi.org/10.4081/monaldi.2024.2991
Hematological and clinical profiling of chronic obstructive pulmonary disease: a comprehensive study
Submitted: March 14, 2024
Accepted: August 9, 2024
Published: September 30, 2024
Accepted: August 9, 2024
Abstract Views: 223
PDF_EARLY VIEW: 75
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Chronic obstructive pulmonary disease (COPD) presents as a multifaceted clinical landscape with various hematological manifestations. Among these, polycythemia and anemia pose distinct challenges. While the prevalence of polycythemia has decreased in recent years, anemia remains a prevalent concern, impacting patient outcomes. This study investigated the incidence and clinical characteristics of polycythemia in COPD patients, focusing on a diverse cohort in India. Methodological approaches included comprehensive evaluations of clinical parameters, pulmonary function, and hematological profiles. Results revealed significant variations in COPD severity, pulmonary function, and respiratory symptoms among patients with different hemoglobin levels. The findings shed light on the complex interplay between hematological variations and clinical manifestations in COPD, providing valuable insights for disease management strategies.
Agustí A, Celli BR, Criner GJ, et al. Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary. Am J Respirat Crit Care Med 2023;207:819-37.
DOI: https://doi.org/10.1164/rccm.202301-0106PP
Vlahakos V, Marathias K, Lionaki S, et al. The paradigm shift from polycythemia to anemia in COPD: the critical role of the renin–angiotensin system inhibitors. Expert Rev Respir Med 2022;16:391-8.
DOI: https://doi.org/10.1080/17476348.2022.2045958
Kollert F, Tippelt A, Müller C, et al. Hemoglobin levels above anemia thresholds are maximally predictive for long-term survival in COPD with chronic respiratory failure. Respir Care 2013;58:1204-12.
DOI: https://doi.org/10.4187/respcare.01961
Shujaat A, Minkin R, Eden E. Pulmonary hypertension and chronic cor pulmonale in COPD. Int J Chron Obstruct Pulmon Dis 2007;2:273-82.
Chambellan A, Chailleux E, Similowski T. Prognostic value of the hematocrit in patients with severe COPD receiving long-term oxygen therapy. Chest 2005;128:1201-8.
DOI: https://doi.org/10.1378/chest.128.3.1201
Alkhedaide AQ. Tobacco smoking causes secondary polycythemia and a mild leukocytosis among heavy smokers in Taif City in Saudi Arabia. Saudi J Biol Sci 2020;27:407-11.
DOI: https://doi.org/10.1016/j.sjbs.2019.11.001
McMullin M, Harrison C, Ali S, et al. A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline. Br J Haematol 2018;184:176-91.
DOI: https://doi.org/10.1111/bjh.15648
Rimal S, Das SK, Basnet A, et al. Prevalence and clinical impact of anemia in patients diagnosed with chronic obstructive pulmonary disease: a cross‐sectional study. Health Sci Rep 2023;6:e1371.
DOI: https://doi.org/10.1002/hsr2.1371
Balasubramanian A, Henderson RJ, Putcha N, et al. Haemoglobin as a biomarker for clinical outcomes in chronic obstructive pulmonary disease. ERJ Open Res 2021;7:00068-2021.
DOI: https://doi.org/10.1183/23120541.00068-2021
Ganesh M S, Satheesh S, Aravindhan S. Insights into the pathophysiology and therapeutic targets of consequences induced by polycythemia in COPD. Biotech Res Asia 2023;20.
DOI: https://doi.org/10.13005/bbra/3170
Zielinski J, Tobiasz M, Hawrylkiewicz I, et al. Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients: a 6-year prospective study. Chest 1998;113:65-70.
DOI: https://doi.org/10.1378/chest.113.1.65
Zhang J, DeMeo DL, Silverman EK, et al. Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors. BMC Pulm Med 2021;21:235.
DOI: https://doi.org/10.1186/s12890-021-01585-5
Masa JF, Pépin JL, Borel JC, et al. Obesity hypoventilation syndrome. Eur Respir Rev 2019;28:180097.
DOI: https://doi.org/10.1183/16000617.0097-2018
Semenza GL. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology 2009;24:97-106.
DOI: https://doi.org/10.1152/physiol.00045.2008
Pahal P, Hashmi MF, Sharma S. Chronic obstructive pulmonary disease compensatory measures. Treasure Island, FL, USA: StatPearls Publishing; 2024.
Sarkar M, Rajta PN, Khatana J. Anemia in chronic obstructive pulmonary disease: prevalence, pathogenesis, and potential impact. Lung India 2015;32:142-51.
DOI: https://doi.org/10.4103/0970-2113.152626
Kayrak M, Acar K, Gul EE, et al. Electrocardiographic findings in patients with polycythemia vera. Int J Med Sci 2012;9:93-102.
DOI: https://doi.org/10.7150/ijms.9.93
Ethics Approval
This study was approved by Institute Ethics Committee. All the patients were recruited in the study only after obtaining proper consent from the patients or their representatives (NITRD/PGEC/2019/5172).How to Cite
Sharma, Amit, Deepak Rathi, Prerna Jain, and Devika Tayal. 2024. “Hematological and Clinical Profiling of Chronic Obstructive Pulmonary Disease: A Comprehensive Study”. Monaldi Archives for Chest Disease, September. https://doi.org/10.4081/monaldi.2024.2991.
Copyright (c) 2024 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Sara Di Michele, Vito Maurizio Parato, Giovanna Di Giannuario, Naji Kholaif, Mohammed Al Admawi, Saif Aljheish, Lana Arbili, Amal Alshammari, Andrea Giovanni Parato, Hani Al Sergani, Unlocking insights in bicuspid aortic valve management in adult patients: the vital role of cardiac imaging , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Vito Maurizio Parato, Sara Belleggia, Andrea Giovanni Parato, Umberto Ianni, Michela Molisana, Germana Gizzi, Simone D'Agostino, Melissa Dottori, Marco Di Eusanio, Multi-valve Libman-Sacks’s endocarditis-related multiple, massive and fatal systemic embolization. A case report and a review of diagnostic work-up , Monaldi Archives for Chest Disease: Early Access
- Diana Alexandra Gonçalves Pimenta, Renata Carvalho, Raquel Pereira, Rui Rolo, Lurdes Ferreira, Interstitial nephritis secondary to treatment with pembrolizumab, a rare complication in two patients with lung adenocarcinoma , Monaldi Archives for Chest Disease: Vol. 93 No. 2 (2023)
- Davide Tarello, Francesca Giogà, Andrea Lauterio, Chiara Becchetti, Giovanni Perricone, Giorgio Santi, Monica Ragazzi, Gianpaola Monti, Marta Lazzeri, Respiratory and physical therapy in the intensive care unit after liver transplantation for acute-on-chronic liver failure: a case report , Monaldi Archives for Chest Disease: Early Access
- Amit Harshana, Mohit Goyal, Augustine Chako, Raman Mahajan, Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in Southeast Asia: a systematic review and meta-analysis , Monaldi Archives for Chest Disease: Early Access
- Navdeep Kaur, Amandeep Kaur, Harvinder Singh Chhabra, Bull’s eye sign – A diagnostic clinch in COVID-19 pneumonia , Monaldi Archives for Chest Disease: Vol. 92 No. 1 (2022)
- Avneet Garg, Rakendra Singh, Hariharan Iyer, Mansimranjit Kaur, Surbhi Surbhi, Ashish Jindal, Saranpal Singh, Avtar Singh Bansal, Hem C. Sati, Vinita Jindal, To study heterogeneity in SARS-CoV-2 IgG response titre in patients recovered from COVID-19 , Monaldi Archives for Chest Disease: Vol. 92 No. 2 (2022)
- Emmanouil Panagiotou, Ioannis Vamvakaris, Nikolaos K. Syrigos, Elias Kotteas, Pulmonary benign metastasizing leiomyoma: a case report , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Sumita Agrawal, Akhil Dhanesh Goel, Nitesh Gupta, Ayush Lohiya, Role of low dose computed tomography on lung cancer detection and mortality - an updated systematic review and meta-analysis , Monaldi Archives for Chest Disease: Vol. 93 No. 1 (2023)
- Madoka Ito, Naoto Ishimaru, Toshio Shimokawa, Yoshiyuki Kizawa, Risk factors for mortality in aspiration pneumonia: a single-center retrospective observational study , Monaldi Archives for Chest Disease: Vol. 93 No. 3 (2023)
<< < 60 61 62 63 64 65 66 67 68 69 > >>
You may also start an advanced similarity search for this article.
