https://doi.org/10.4081/monaldi.2024.3140
Comparison of diagnostic yield and safety of endobronchial ultrasound-guided mediastinal lymph nodal cryobiopsy and endobronchial ultrasound-guided Franseen tip needle biopsy
Submitted: July 18, 2024
Accepted: September 27, 2024
Published: December 6, 2024
Accepted: September 27, 2024
Abstract Views: 93
PDF_EARLY VIEW: 27
SUPPLEMENTARY MATERIAL: 7
SUPPLEMENTARY MATERIAL: 7
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
In this prospective study, we evaluated the diagnostic yield and safety of two endobronchial ultrasound (EBUS) biopsy techniques – mediastinal cryobiopsy (EBUS-MCB) and Franseen tip needle biopsy (EBUS-ANB) – in patients with undiagnosed mediastinal lymphadenopathy. The study included 30 patients who underwent both EBUS-MCB and EBUS-ANB, with four biopsies taken from each patient using both methods. The results demonstrated that EBUS-MCB provided a higher diagnostic yield (96.4%) compared to EBUS-ANB (73.3%). Specimens from EBUS-MCB showed fewer artifacts and a higher density of granulomas and were adequate for ancillary studies in all cases. The most common complication observed was minor bleeding, which was more common with EBUS-MCB (36.6% versus 13.3%, p=0.04). This study demonstrates that EBUS-guided cryobiopsy has a higher diagnostic yield when compared to EBUS-guided Franseen tip needle biopsy and that both biopsy techniques have an acceptable safety profile. Larger studies comparing these two techniques are necessary to confirm the findings of the current study.
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Ethics Approval
The study protocol was approved by the Ethical Review Committee of Yashoda Super Specialty Hospitals (IRB No: RP/01/2023) on 18/01/2023.How to Cite
Maturu, Venkata Nagarjuna, Anand Vijay, Virender Pratibh Prasad, Rinoosha Rechal, Vipul Kumar Garg, and Shweta Sethi. 2024. “Comparison of Diagnostic Yield and Safety of Endobronchial Ultrasound-Guided Mediastinal Lymph Nodal Cryobiopsy and Endobronchial Ultrasound-Guided Franseen Tip Needle Biopsy”. Monaldi Archives for Chest Disease, December. https://doi.org/10.4081/monaldi.2024.3140.
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