Novel tuberculosis skin tests for detecting latent tuberculosis infection

Submitted: July 28, 2024
Accepted: September 16, 2024
Published: November 4, 2024
Abstract Views: 146
PDF_EARLY VIEW: 58
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Authors

Dear Editor,

We are impressed by the article titled “Latent tuberculosis diagnostics: current scenario and review” by Gupta et al. published in your journal. The authors have reviewed the tests used for diagnosis of latent tuberculosis infection and have given a detailed overview of the purified protein derivative-based tuberculin skin test and interferon γ release assays. We would like to draw attention to the fact that in 2022, the World Health Organization has also recommended the use of Mycobacterium tuberculosis antigen-based skin tests for the diagnosis of latent tuberculosis (conditional recommendation, very low certainty of evidence).

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Citations

Gupta A, Chandra E, Anand S, et al. Latent tuberculosis diagnostics: current scenario and review. Monaldi Arch Chest Dis 2024; doi: 10.4081/monaldi.2024.2984. DOI: https://doi.org/10.4081/monaldi.2024.2984
WHO. WHO consolidated guidelines on tuberculosis. Module 3: diagnosis. Tests for TB infection. Available from: https://iris.who.int/bitstream/handle/10665/362936/9789240056084-eng.pdf?sequence=1.
Krutikov M, Faust L, Nikolayevskyy V, et al. The diagnostic performance of novel skin-based in-vivo tests for tuberculosis infection compared with purified protein derivative tuberculin skin tests and blood-based in vitro interferon-γ release assays: a systematic review and meta-analysis. Lancet Infect Dis 2022;22:250-64. DOI: https://doi.org/10.1016/S1473-3099(21)00261-9
Badaro R, Machado BAS, Duthie MS, et al. The single recombinant M. tuberculosis protein DPPD provides enhanced performance of skin testing among HIV-infected tuberculosis patients. AMB Express 2020;10:133. DOI: https://doi.org/10.1186/s13568-020-01068-6

How to Cite

Doshi, Jinish, Kunal Deokar, and Priyanka Gaikwad. 2024. “Novel Tuberculosis Skin Tests for Detecting Latent Tuberculosis Infection”. Monaldi Archives for Chest Disease, November. https://doi.org/10.4081/monaldi.2024.3156.

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