https://doi.org/10.4081/monaldi.2025.3246
Effect of high flow nasal cannula versus conventional nasal cannula oxygen therapy in patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration
Accepted: December 18, 2024
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Patients undergoing endobronchial ultrasound-guided fine needle aspiration may have multiple comorbidities, contributing to higher risks of hypoxia and adverse events, such as arrhythmias. The current study compared the efficacy of two oxygenation modalities: the high-flow nasal cannula (HFNC) vs. conventional oxygen therapy (CNC). Patients were randomized to either the HFNC or the CNC arm. HFNC and CNC were initiated and escalated as per predefined protocols. The number of desaturation events [fall in saturation of peripheral oxygen (SpO2) by 3% from the baseline] and change in levels of transcutaneous CO2 (tcCO2) from baseline were noted. Subgroup analysis was done in patients with cardiopulmonary comorbidities and in patients with SpO2<97%. A total of 122 patients were randomized. Overall, there was no significant difference in the number of desaturation events and change in tcCO2 levels; however, in patients with cardiopulmonary comorbidities (obstructive sleep apnea, heart diseases, and stable chronic obstructive airway disease), 50% in the HFNC arm had no desaturation compared to 11.7% in the CNC arm (p=0.007). 41.17% of patients in the HFNC arm had a rise in tcCO2 levels, compared to 36.11% of patients in the CNC arm (p>0.5). In patients with SpO2<97%, 48.88% in the HFNC arm had no desaturations compared to 14.70% in the CNC arm (p=0.001); there was no statistical difference in rise in tcCO2. Hence, HFNC would be a better modality for oxygenation in patients with a high risk of hypoxia without increasing the risk of hypercapnia.
Ethics Approval
Ethical clearance taken from the Institutional Ethics Committee, VMMC, and Safdarjung Hospital, New Delhi with serial no IEC/VMMC/SJH/Thesis/9/2022/CC-14, dated 6/10/2022.How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Ram Niwas, Gopal Chawla, Puneet Pareek, Nishant Kumar Chauhan, Naveen Dutt, Revisiting bronchoscopic intratumoral chemotherapy in malignant central airway obstruction via EUS-B approach and its review of literature , Monaldi Archives for Chest Disease: Vol. 90 No. 4 (2020)
- U. Caterino, G. Dialetto, F.E. Covino, G. Mazzarella, E. Grella, M. Massimo, The usefulness of transesophageal echocardiography in the staging of locally advanced lung cancer , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- G.C. Maglaras, S. Katsenos, J. Kakadelis, C. Katsanos, Z. Metafratzi, D.G. Stefanou, M.P. Vassiliou, S.H. Constantopoulos, Primary angiosarcoma of the lung and pleura , Monaldi Archives for Chest Disease: Vol. 61 No. 4 (2004): Pulmonary series
- Muhammed Kurt, Udo Boeken, Jens Litmathe, Peter Feindt, Emmeran Gams, Oxygenation failure after cardiac surgery: early re-intubation versus treatment by nasal continuous positive airway pressure (NCPAP) or non-invasive positive pressure ventilation (NPPV) , Monaldi Archives for Chest Disease: Vol. 70 No. 2 (2008): Cardiac series
- C. Robalo Cordeiro, S. Freitas, B. Rodrigues, A. Catarino, M.J. Matos, I. Ferreira, L. Carvalho, Diagnosis of Respiratory Bronchiolitis associated interstitial lung disease , Monaldi Archives for Chest Disease: Vol. 65 No. 2 (2006): Pulmonary series
- Sergio Baldi, Francesco Coni, Giorgio Limerutti, Massimo Baccega, Enrico Ruffini, Paolo Solidoro, Delayed functional improvement after near-fatal bleeding complication following endobronchial valve therapy for emphysema , Monaldi Archives for Chest Disease: Vol. 81 No. 1-2 (2015): Pulmonary series
- Carmine Guarino, Cristiano Cesaro, Giuseppe La Cerra, Raffaella Lucci, Flavio Cesaro, Enzo Zamparelli, Gianfranco Gaglione, Agostina Pontarelli, Annunziata De Rosa, Roberto Parrella, Endobronchial hamartoma in a young COVID-19 symptomatic woman. Radical endoscopic treatment with a disposable bronchoscope. Case Report , Monaldi Archives for Chest Disease: Vol. 92 No. 3 (2022)
- Venugopal Jaganathan, Santhakumar Subramanian, Deepak T Hari, Recurrent tracheal tumor with a critical airway requiring ‘Y’ stent – unique presentation of tuberculosis , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
- C. Carbonelli, S. Montepietra, A. Caruso, A. Cavazza, C. Feo, F. Menzella, L. Motti, L. Zucchi, Sarcoidosis and multiple sclerosis: systemic toxicity associated with the use of interferon-beta therapy , Monaldi Archives for Chest Disease: Vol. 77 No. 1 (2012): Pulmonary series
- G. Callegari, C. Fracchia, Lung Transplantation and Endoscopic Issues , Monaldi Archives for Chest Disease: Vol. 75 No. 1 (2011): Pulmonary series
<< < 5 6 7 8 9 10 11 12 13 14 > >>
You may also start an advanced similarity search for this article.
