https://doi.org/10.4081/monaldi.2025.3278
Prevalence and impact of anxiety and depression in patients with chronic obstructive pulmonary disease: a comparative analysis of post-tuberculosis and non-tuberculosis chronic obstructive pulmonary disease cases
Submitted: November 28, 2024
Accepted: January 9, 2025
Published: March 3, 2025
Accepted: January 9, 2025
Abstract Views: 349
PDF_EARLY VIEW: 80
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Chronic obstructive pulmonary disease (COPD) is a prevalent and debilitating condition, increasingly recognized for its complex interaction with psychiatric disorders such as anxiety and depression. This study assesses and compares the prevalence of anxiety and depression among COPD patients, including those with a history of pulmonary tuberculosis (TB), and examines their associations with COPD severity. This descriptive, cross-sectional study included 100 patients diagnosed with COPD, aged 40 to 80 years. Patients underwent comprehensive clinical evaluation, including spirometry and COPD assessment tests, and were assessed for anxiety and depression using the Hospital Anxiety and Depression Scale. Participants were classified based on their COPD status and history of TB. Data on sociodemographic and clinical characteristics was collected, and associations between psychiatric illnesses and COPD status were analyzed. The study population was predominantly male (73%), with a mean age of 56.33 years. The COPD assessment score was medium in 65% of participants, with 30% of patients exhibiting high levels. Anxiety was present in 21% of the cohort, while 30% had depression. Analysis revealed a significant association between high COPD scores and increased prevalence of both anxiety and depression (p<0.05). Additionally, patients with a history of pulmonary TB showed higher rates of psychiatric comorbidities. Specifically, anxiety was more prevalent among patients with severe COPD and a history of TB. These findings highlight a substantial burden of anxiety and depression among COPD patients, particularly those with severe disease and a history of TB. These results align with the existing literature, suggesting a strong link between COPD severity, psychiatric comorbidities, and the impact of historical TB on mental health. These insights underscore the need for integrated management strategies addressing both respiratory and psychiatric aspects of COPD care.
Rabe KF, Hurd S, Anzueto A, et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007;176:532-55.
DOI: https://doi.org/10.1164/rccm.200703-456SO
World Health Organization. Chronic obstructive pulmonary disease (COPD). 2024. Available from: https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd). Accessed on: 8/11/2024.
Chatila WM, Thomashow BM, Minai OA, et al. Comorbidities in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5:549-55.
DOI: https://doi.org/10.1513/pats.200709-148ET
Tsiligianni IG, Kosmas E, Van der Molen T, Tzanakis N. Managing comorbidity in COPD: a difficult task. Curr Drug Targets 2013;14:158-76.
DOI: https://doi.org/10.2174/1389450111314020004
Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Available from: https://goldcopd.org/. Accessed on: 8/11/2024.
Koskela J, Kilpeläinen M, Kupiainen H, et al. Co-morbidities were the key nominators of the health-related quality of life in mild and moderate COPD. BMC Pulm Med 2014;14:102.
DOI: https://doi.org/10.1186/1471-2466-14-102
Celli BR, MacNee W, ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004;23:932-46.
DOI: https://doi.org/10.1183/09031936.04.00014304
Willgoss TG, Yohannes AM. Anxiety disorders in patients with COPD: a systematic review. Respir Care 2013;58:858-66.
DOI: https://doi.org/10.4187/respcare.01862
Biswas D, Mukherjee S, Chakroborty R, et al. Occurrence of anxiety and depression among stable COPD patients and its impact on functional capability. J Clin Diagnostic Res 2017;11:OC24-7.
DOI: https://doi.org/10.7860/JCDR/2017/24203.9393
Maurer J, Rebbapragada V, Borson S, et al. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 2008;134:43S-56S.
DOI: https://doi.org/10.1378/chest.08-0342
Dowson C, Laing R, Barraclough R, et al. The use of the hospital anxiety and depression scale (HADS) in patients with chronic obstructive pulmonary disease: a pilot study. N Z Med J 2001;114:447-9.
Yohannes AM, Willgoss TG, Baldwin RC, Connolly MJ. Depression and anxiety in chronic heart failure and chronic obstructive pulmonary disease: prevalence, relevance, clinical implications and management principles. Int J Geriatr Psychiatry 2010;25:1209-21.
DOI: https://doi.org/10.1002/gps.2463
Gudmundsson G, Gislason T, Janson C, et al. Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression. Eur Respir J 2005;26:414-9.
DOI: https://doi.org/10.1183/09031936.05.00078504
Ng TP, Niti M, Tan WC, et al. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med 2007;167:60-7.
DOI: https://doi.org/10.1001/archinte.167.1.60
Dahlén I, Janson C. Anxiety and depression were related to the outcome of emergency treatment in patients with obstructive pulmonary disease. Chest 2002;122:1633-7.
DOI: https://doi.org/10.1378/chest.122.5.1633
Mishima M, Oku Y, Muro S, et al. Relationship between dyspnea in daily life and psycho-physiologic state in patients with chronic obstructive pulmonary disease during long-term domiciliary oxygen therapy. Intern Med 1996;35:453-8.
DOI: https://doi.org/10.2169/internalmedicine.35.453
Katare S, Harsha A. Correlations between inflammatory biomarkers in tuberculosis-associated obstructive pulmonary disease patients with anxiety and depression. Cureus 2022;14:e22742.
DOI: https://doi.org/10.7759/cureus.22742
van Manen JG, Bindels PJ, Dekker FW, et al. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax 2002;57:412-6.
DOI: https://doi.org/10.1136/thorax.57.5.412
Lacasse Y, Rousseau L, Maltais F. Prevalence of depressive symptoms and depression in patients with severe oxygendependent chronic obstructive pulmonary disease. J Cardiopulm Rehabil 2001;21:80-6.
DOI: https://doi.org/10.1097/00008483-200103000-00004
Yohannes AM, Baldwin RC, Connolly MJ. Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence, and validation of the BASDEC screening questionnaire. Int J Geriatr Psychiatry 2000;15:1090-6.
DOI: https://doi.org/10.1002/1099-1166(200012)15:12<1090::AID-GPS249>3.0.CO;2-L
Yohannes AM, Baldwin RC, Connolly MJ. Prevalence of sub-threshold depression in elderly patients with chronic obstructive pulmonary disease. Int J Geriatr Psychiatry 2003;18:412-6.
DOI: https://doi.org/10.1002/gps.851
Cully JA, Graham DP, Stanley MA, et al. Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression. Psychosomatics 2006;47:312-9.
DOI: https://doi.org/10.1176/appi.psy.47.4.312
Rahi MS, Thilagar B, Balaji S, et al. The impact of anxiety and depression in chronic obstructive pulmonary disease. Adv Respir Med 2023;91:123-34.
DOI: https://doi.org/10.3390/arm91020011
Ethics Approval
Ethics approval was obtained from the ethics committee of the institute (BSA/234/2021).How to Cite
Chandra, Eshutosh, Shipra Anand, Amitesh Gupta, Roopam Jha, and Irshad Ahmad. 2025. “Prevalence and Impact of Anxiety and Depression in Patients With Chronic Obstructive Pulmonary Disease: A Comparative Analysis of Post-Tuberculosis and Non-Tuberculosis Chronic Obstructive Pulmonary Disease Cases”. Monaldi Archives for Chest Disease, March. https://doi.org/10.4081/monaldi.2025.3278.
Copyright (c) 2025 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- S.M. Mirsaeidi, P. Tabarsi, A. Mardanloo, G. Ebrahimi, M. Amiri, P. Farnia, M. Sheikhleslami, V. Bakayev, F. Mohammadi, S.D. Mansouri, M.R. Masjedi, A.A. Velayati, Pulmonary Mycobacterium Simiae infection and HTLV1 infection: an incidental co-infection or a predisposing factor? , Monaldi Archives for Chest Disease: Vol. 65 No. 2 (2006): Pulmonary series
- Raffaele Griffo, Antonio Spanevello, Pier Luigi Temporelli, Pompilio Faggiano, Mauro Carone, Giovanna Magni, Nicolino Ambrosino, Luigi Tavazzi, Italian survey on prevalence and disease management of chronic heart failure and chronic obstructive pulmonary disease comorbidity in ambulatory patients. SUSPIRIUM study rationale and design , Monaldi Archives for Chest Disease: Vol. 82 No. 1 (2014): Cardiac series
- Madalina Macrea, Richard ZuWallack, Linda Nici, There’s no place like home: Integrating pulmonary rehabilitation into the home setting , Monaldi Archives for Chest Disease: Vol. 87 No. 2 (2017)
- Rosa Spezzaferri, Maddalena Modica, Vittorio Racca, Vittorino Ripamonti, Monica Tavanelli, Gabriella Brambilla, Maurizio Ferratini, Psychological disorders after coronary artery by-pass surgery: a one-year prospective study , Monaldi Archives for Chest Disease: Vol. 72 No. 4 (2009): Cardiac series
- L. Moroni, O. Bettinardi, G. Vidotto, G. Balestroni, G. Bruletti, I. Giorgi, G. Bertolotti, Anxiety and Depression Short Scale: norms for its use in rehabilitation , Monaldi Archives for Chest Disease: Vol. 66 No. 4 (2006): Cardiac series
- Floriana Caccamo, Simone Saltini, Enrico Carella, Roberto Carlon, Cristina Marogna, Vito Sava, The measure of effectiveness of a short-term 2-week intensive Cardiac Rehabilitation program in decreasing levels of anxiety and depression , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Claudio F. Donner, Sandro Amaducci, Elena Bacci, Sandra Baldacci, Maria L. Bartoli, Gianfranco M. Beghi, Alida Benfante, Sara Brighindi, Lucio Casali, Daniela Castiglia, Mario Cazzola, Alessandro Celi, Silvana Cianchetti, Giorgio Colombo, Claudia Crimi, Federico L. Dente, Giuseppe Di Maria, Annalisa Di Maria, Manuela Latorre, Federico Lavorini, Sara Maio, Claudia Mannini, Riccardo Messina, Pier Luigi Paggiaro, Patrizia Pignatti, David Price, Nicola Scichilone, Marzia Simoni, Antonio Spanevello, Martina Stagno d’Alcontres, Shawna Tan, Roberto Torchio, Giovanni Viegi, Dina Visca, Emiel F.M. Wouters, Shaylynn Yu Hui Xin, Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- M. Lusuardi, C. Lucioni, F. De Benedetto, S. Mazzi, C.M. Sanguinetti, C.F. Donner, GOLD severity stratification and risk of hospitalisation for COPD exacerbations , Monaldi Archives for Chest Disease: Vol. 69 No. 4 (2008): Pulmonary series
- Marinella Sommaruga, Elisabetta Angelino, Paola Della Porta, Mara Abatello, Giacomo Baiardo, Gianluigi Balestroni, Ornella Bettinardi, Edward Callus, Chiara Ciracì, Ombretta Omodeo, Claudia Rizza, Paolo Michielin, Marco Ambrosetti, Raffaele Griffo, Roberto F.E. Pedretti, Antonia Pierobon, Best practice in psychological activities in cardiovascular prevention and rehabilitation: Position Paper , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Elio Gorga, Marta Scodro, Francesca Valentini, Renzo D'Ortona, Mariachiara Arisi, Edoardo Sciatti, Ivano Bonadei, Valentina Regazzoni, Enrico Vizzardi, Marco Metra, Piergiacomo Calzavara Pinton, Echocardiographic evaluation of diastolic dysfunction in young and healthy patients with psoriasis: A case-control study , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
