https://doi.org/10.4081/monaldi.2005.642

Bronchial hyperreactivity and spirometric impairment in patients with allergic rhinitis

Vol. 63 No. 2 (2005): Pulmonary series
Submitted: February 18, 2016
Accepted: February 18, 2016
Published: June 30, 2005
Seasonal allergic rhinitis, perennial allergic rhinits, polysensitized patients, bronchial hyperreactivity, methacholine challenge, bronchial obstruction
Abstract Views: 739
PDF: 412
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

I. Cirillo
gio.cip@libero.it
Ospedale Principale della Marina Militare, Reparto di Medicina, Allergologia e Fisiopatologia Respiratoria, La Spezia, Italy.
A. Vizzaccaro
Ospedale Principale della Marina Militare, Reparto di Medicina, Allergologia e Fisiopatologia Respiratoria, La Spezia, Italy.
M.A. Tosca
Istituto Giannina Gaslini, Genova, Italy.
S. Negrini
Dipartimento di Medicina Interna, Università di Genova, Italy.
A.C. Negrini
Primario Emerito di Allergologia, Ospedale San Martino di Genova, Italy.
G. Marseglia
Clinica Pediatrica, IRCCS Policlinico San Matteo, Pavia, Italy.
G. Ciprandi
Unità di Allergologia, Dipartimento Testa-Collo, Ospedale San Martino di Genova, Italy.
Background: The Link between allergic rhinitis and asthma is well known. Bronchial hyperreactivity (BHR) may be present in rhinitics. The present study is aimed at evaluating a large group of subjects suffering from allergic rhinitis alone to investigate the presence of spirometric impairment and BHR both during and outside the pollen season. Methods: 360 rhinitics (subdivided in 3 groups: seasonal, SAR, perennial, PAR, and polysensitized, PolysR) were investigated by spirometry and methacholine challenge. Results: There was a significant seasonal difference concerning the number of rhinitics with impaired FEV1 (p<0.01 for SAR, p<0.02 for PAR, and p<0.03 for PolysR) and FEF25-75 (p<0.05 for SAR, p<0.03 for PAR, and p<0.05 for PolysR) as well as with BHR (p<0.05 for SAR and p<0.03 for PAR). Conclusions: This study evidences that an impairment of spirometric parameters and BHR may be observed in patients with allergic rhinitis alone. Thus, careful evaluation of lower airways should be performed in patients with allergic rhinitis alone.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

How to Cite

Cirillo, I., A. Vizzaccaro, M.A. Tosca, S. Negrini, A.C. Negrini, G. Marseglia, and G. Ciprandi. 2005. “Bronchial Hyperreactivity and Spirometric Impairment in Patients With Allergic Rhinitis”. Monaldi Archives for Chest Disease 63 (2). https://doi.org/10.4081/monaldi.2005.642.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.