https://doi.org/10.4081/monaldi.2016.721
Phenomenology of COPD: interpreting phenotypes with the ECLIPSE study
Accepted: July 5, 2016
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) study was a large 3-year observational multicentre international study aimed at defining COPD phenotypes and identifying biomarkers and/or genetic parameters that help to predict disease progression. The study has contributed to a better understanding of COPD heterogeneity, with the characterization of clinically important subtypes/phenotypes of patients, such as the frequent exacerbators or patient with persistent systemic inflammation, who may have different prognosis or treatment requirements. Because of the big amount of information that is starting to be produced from metabolomic, proteomic and genomic approaches, one of the biggest challenges is the integration of data in a biological prospective such as clinical prognosis and response to medicinal products. In this article we highlight some of the progress in phenotyping the heterogeneity of the disease that have been made thanks to the analyses of this longitudinal study.
Supporting Agencies
GlaxoSmithKlineHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Lucrezia De Michele, Paola Pierucci, Guido Giovannetti, Michele De Ceglie, Michela Dimitri, Alessandra Mirabile, Vitaliano Quaranta, Arnaldo Scardapane, Carlo D'Agostino, Giovanna Elisiana Carpagnano, Post severe COVID-19 infection lung damages study. The experience of early three months multidisciplinary follow-up , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Ananda Datta, Satya Padmaja Mantha, Suvradeep Mitra, Prasanta Raghab Mohapatra, M Srikanth Goud, Manoj Kumar Panigrahi, ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman , Monaldi Archives for Chest Disease: Vol. 90 No. 3 (2020)
- Alberto Fantin, Nadia Castaldo, Paolo Vailati, Giuseppe Morana, Vincenzo Patruno, Full medical treatment of COVID-19 associated large pneumothorax - A case report , Monaldi Archives for Chest Disease: Vol. 92 No. 1 (2022)
- Ahmed Ghanaym, Khaled Elkhashab, Gomaa AbdelRazek, Eman Mahmoud, Evaluation of left atrial dysfunction by speckle tracking echocardiography in systolic and diastolic heart failure , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Emmanouil Panagiotou, Ioannis Vamvakaris, Nikolaos K. Syrigos, Elias Kotteas, Pulmonary benign metastasizing leiomyoma: a case report , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Diana Alexandra Gonçalves Pimenta, Renata Carvalho, Raquel Pereira, Rui Rolo, Lurdes Ferreira, Interstitial nephritis secondary to treatment with pembrolizumab, a rare complication in two patients with lung adenocarcinoma , Monaldi Archives for Chest Disease: Vol. 93 No. 2 (2023)
- Lilit Khachatryan, Ruzanna Grigoryan, Andrei Dadu, Ajay M.V. Kumar, Kristina Akopyan, Kostyantyn Dumchev, Hasmik Harutyunyan, Alberto Matteelli, Factors associated with unfavourable treatment outcomes among people with rifampicin-resistant tuberculosis in Armenia, 2014-2017 , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Karrar Al-Buthabhak , Hussein Nafakhi, Mohammed H. Shukur , Ahmed Nafakhi, Mohammed Alareedh, Foaad Shaghee, Blood indices, in-hospital outcome and short-term prognosis in patients with COVID-19 pneumonia , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Mariana Buziashvili, Hayk Davtyan, Yuliia Sereda, Olga Denisiuk, Ogtay Gozalov, Nino Lomtadze, Arax Hovhannesyan, Incidence rate and time to serious adverse events among rifampicin resistant tuberculosis patients in Georgia treated with new and repurposed anti-tuberculosis drugs, 2016-2018 , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Matteo Petroncini, Leonardo Valentini, Piergiorgio Solli, Pietro Bertoglio, Giant lung bulla as a late-onset complication of mild SARS-CoV-2 pneumonia , Monaldi Archives for Chest Disease: Vol. 94 No. 3 (2024)
<< < 30 31 32 33 34 35 36 37 38 39 > >>
You may also start an advanced similarity search for this article.
