https://doi.org/10.4081/monaldi.2016.721
Phenomenology of COPD: interpreting phenotypes with the ECLIPSE study
Accepted: July 5, 2016
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) study was a large 3-year observational multicentre international study aimed at defining COPD phenotypes and identifying biomarkers and/or genetic parameters that help to predict disease progression. The study has contributed to a better understanding of COPD heterogeneity, with the characterization of clinically important subtypes/phenotypes of patients, such as the frequent exacerbators or patient with persistent systemic inflammation, who may have different prognosis or treatment requirements. Because of the big amount of information that is starting to be produced from metabolomic, proteomic and genomic approaches, one of the biggest challenges is the integration of data in a biological prospective such as clinical prognosis and response to medicinal products. In this article we highlight some of the progress in phenotyping the heterogeneity of the disease that have been made thanks to the analyses of this longitudinal study.
Supporting Agencies
GlaxoSmithKlineHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- C.A. Lindemans, R.A. Bruinsma, P.G.J. Nikkels, F.H.L. Bröker, H.G.M. Arets, Pulmonary consolidation and inflammation: inflammatory pseudotumour in young children , Monaldi Archives for Chest Disease: Vol. 71 No. 2 (2009): Pulmonary series
- Cuneyt Tetikkurt, Halil Yanardag, Metin Pehlivan, Muammer Bilir, Clinical features and prognostic significance of splenic involvement in sarcoidosis , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Sunil K. Chhabra, Devi Jyoti Dash, Concurrent sensitization to Aspergillus Fumigatus in tropical pulmonary eosinophilia , Monaldi Archives for Chest Disease: Vol. 81 No. 1-2 (2015): Pulmonary series
- S. Ayık, A. Çakan, N. Aslankara, A. Özsöz, Tuberculous abscess on the chest wall , Monaldi Archives for Chest Disease: Vol. 71 No. 1 (2009): Pulmonary series
- G.F. Milani, C. Simonassi, M. Salio, Palliative Therapy , Monaldi Archives for Chest Disease: Vol. 75 No. 1 (2011): Pulmonary series
- Francesco Giallauria, Neil Andrew Smart, Antonio Cittadini, Carlo Vigorito, Exercise training modalities in chronic heart failure: does high intensity aerobic interval training make the difference? , Monaldi Archives for Chest Disease: Vol. 86 No. 1-2 (2016): Cardiac series
- Giuseppe Calsamiglia, Federica Camera, Antonio Mazza, Paola Villa, Francesca Gigli Berzolari, Roberto Tramarin, Franco Cobelli, A new test (VITTORIO Test) for functional fitness assessment in rehabilitation after cardiac surgery , Monaldi Archives for Chest Disease: Vol. 64 No. 1 (2005): Cardiac series
- C.M. Sanguinetti, F. De Benedetto, C.F. Donner, GP management of community-acquired pneumonia in Italy: the ISOCAP study , Monaldi Archives for Chest Disease: Vol. 63 No. 1 (2005): Pulmonary series
- U. Yilmaz, G. Polat, N. Sahin, Ö. Soy, U. Gülay, CT in differential diagnosis of benign and malignant pleural disease , Monaldi Archives for Chest Disease: Vol. 63 No. 1 (2005): Pulmonary series
- F. Chiappini, A. Zoli, L. Maugeri, Pulmonary involvement in systemic sclerosis due to therapy and as a complication , Monaldi Archives for Chest Disease: Vol. 63 No. 2 (2005): Pulmonary series
<< < 33 34 35 36 37 38 39 40 41 42 > >>
You may also start an advanced similarity search for this article.
