https://doi.org/10.4081/monaldi.2018.954
Prognostic impact of digoxin use for rate control of atrial fibrillation in patients ≥75 years of age
Accepted: May 11, 2018
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Digoxin use remains a common therapeutic option in the pharmacological control of heart rate in patients with atrial fibrillation, endorsed in current guidelines with the same level of evidence than beta-blockers in patients with and without heart failure. Digoxin has a narrow therapeutic range and is influenced by drugâ€toâ€drug interactions, serum electrolyte concentrations, and renal function. Conflicting data exist regarding adverse outcomes that are associated with digoxin use in patients with atrial fibrillation. It remains unclear whether the association between digoxin use and worse clinical outcome is causal or may be the result of confounding by differences in the characteristics of patents including age, comorbidities and treatment. Particularly in older patients with atrial fibrillation, who are frequently prescribed a multitude of agents for stroke prevention, treatment of cardiovascular disease and other comorbidities, use of digoxin should be cautious and instituted with assessment of drug concentrations.
How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Elio Gorga, Marta Scodro, Francesca Valentini, Renzo D'Ortona, Mariachiara Arisi, Edoardo Sciatti, Ivano Bonadei, Valentina Regazzoni, Enrico Vizzardi, Marco Metra, Piergiacomo Calzavara Pinton, Echocardiographic evaluation of diastolic dysfunction in young and healthy patients with psoriasis: A case-control study , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
- Michele Vitacca, Luca Barbano, Daniele Colombo, Olivia Leoni, Enrico Guffanti, Prevalence and variability of use of home mechanical ventilators, positive airway pressure and oxygen devices in the Lombardy region, Italy , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Giovanni Luca Botto, Carlo Piemontese, Giovanni Russo, Rhythm-control vs rate-control in the elderly: When to do it and which drug to prefer? , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Mario Sorice, Francesco Paolo Tritto, Chiara Sordelli, Rosario Gregorio, Luigi Piazza, N-3 polyunsaturated fatty acids reduces post-operative atrial fibrillation incidence in patients undergoing “on-pump†coronary artery bypass graft surgery , Monaldi Archives for Chest Disease: Vol. 76 No. 2 (2011): Cardiac series
- Francesco Orso, Riccardo Barucci, Stefania Fracchia, Giulio Mannarino, Alessandra Pratesi, Francesco Fattirolli, Treatment of very old patients with non valvular atrial fibrillation. The valuable opportunity offered by New Oral Anticoagulants, to be cautiously used , Monaldi Archives for Chest Disease: Vol. 80 No. 4 (2013): Cardiac Series
- Giovanni Capobianco, Cognitive impairment in patients with atrial fibrillation: What is the importance of anticoagulant therapy? , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Maurizio Giuseppe Abrignani, Furio Colivicchi, Thromboembolic and hemorrhagic risk stratification in patients with atrial fibrillation. Part I: the thromboembolic risk , Monaldi Archives for Chest Disease: Vol. 80 No. 2 (2013): Cardiac series
- Stefano Fumagalli, Serena Boni, Simone Pupo, Marta Migliorini, Irene Marozzi, Eleonora Barghini, Flavia Sacco, Niccolò Marchionni, Rate-control vs rhythm-control of atrial fibrillation in elderly patients. From new, age-oriented outcomes to a more complex management strategy , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Roberto Cemin, Massimiliano Manfrin, Massimo Daves, Werner Rauhe, Aldo Pietro Maggioni, Ten years differences in recently onset atrial fibrillation and flutter incidence and management , Monaldi Archives for Chest Disease: Vol. 82 No. 3 (2014): Cardiac series
- Roberta Ancona, Salvatore Comenale Pinto, Pio Caso, Vito Di Palma, Francesca Pisacane, Alfonso Roberto Martiniello, Cesare Quarto, Nicla De Rosa, Carlo Pisacane, Raffaele Calabrò, Right atrial mass following transcatheter radiofrequency ablation for recurrent atrial fibrillation: thrombus, endocarditis or mixoma? , Monaldi Archives for Chest Disease: Vol. 72 No. 1 (2009): Cardiac series
You may also start an advanced similarity search for this article.
