https://doi.org/10.4081/monaldi.2018.954
Prognostic impact of digoxin use for rate control of atrial fibrillation in patients ≥75 years of age
Accepted: May 11, 2018
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Digoxin use remains a common therapeutic option in the pharmacological control of heart rate in patients with atrial fibrillation, endorsed in current guidelines with the same level of evidence than beta-blockers in patients with and without heart failure. Digoxin has a narrow therapeutic range and is influenced by drugâ€toâ€drug interactions, serum electrolyte concentrations, and renal function. Conflicting data exist regarding adverse outcomes that are associated with digoxin use in patients with atrial fibrillation. It remains unclear whether the association between digoxin use and worse clinical outcome is causal or may be the result of confounding by differences in the characteristics of patents including age, comorbidities and treatment. Particularly in older patients with atrial fibrillation, who are frequently prescribed a multitude of agents for stroke prevention, treatment of cardiovascular disease and other comorbidities, use of digoxin should be cautious and instituted with assessment of drug concentrations.
How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- S. Bertini, M. Picariello, M. Gorini, T. Renda, A. Augustynen, G. Villella, G. Misuri, N.M. Maluccio, R. Ginanni, D. Tozzi, A. Corrado, Telemonitoring in chronic ventilatory failure: a new model of survellaince, a pilot study , Monaldi Archives for Chest Disease: Vol. 77 No. 2 (2012): Pulmonary series
- S. Katsenos, M. Nikolopoulou, Intramedullary thoracic spinal metastasis from small-cell lung cancer , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series
- F. Scafa, C.M. Minelli, R. Fonte, G.L. Rosso, M.I. Cappelli, S.M. Candura, Silicotuberculosis in the elderly: report of two cases , Monaldi Archives for Chest Disease: Vol. 61 No. 4 (2004): Pulmonary series
- G. Riccioni, M. De Benedictis, R. Della Vecchia, C. Di Ilio, M.T. Guagnano, N. D’Orazio, Prevalence and severity of airway obstruction in an Italian adult population , Monaldi Archives for Chest Disease: Vol. 63 No. 2 (2005): Pulmonary series
- G.C. Maglaras, S. Katsenos, J. Kakadelis, C. Katsanos, Z. Metafratzi, D.G. Stefanou, M.P. Vassiliou, S.H. Constantopoulos, Primary angiosarcoma of the lung and pleura , Monaldi Archives for Chest Disease: Vol. 61 No. 4 (2004): Pulmonary series
- G. Caramori, M. Fabbri, D. Paioli, F. Falcone, C. Severino, G. Felisatti, O. Arar, I.M. Adcock, K. Fan Chung, P.J. Barnes, A. Ciaccia, A. Papi, Asthma is not a common cause of severe chronic respiratory failure in non-smokers: ALOT study , Monaldi Archives for Chest Disease: Vol. 63 No. 2 (2005): Pulmonary series
- Sergio Baldi, Francesco Coni, Giorgio Limerutti, Massimo Baccega, Enrico Ruffini, Paolo Solidoro, Delayed functional improvement after near-fatal bleeding complication following endobronchial valve therapy for emphysema , Monaldi Archives for Chest Disease: Vol. 81 No. 1-2 (2015): Pulmonary series
- Renzo Rozzini, Aging clinical problems: a difficult balance between age and frailty , Monaldi Archives for Chest Disease: Vol. 84 No. 1-2 (2015): Cardiac series
- Chiara Pedone, Stefano Urbinati, Maria Giovanna Pallotti, Giuseppe Pinelli, Obesity and cardiovascular disease: expected and unexpected relationship , Monaldi Archives for Chest Disease: Vol. 64 No. 1 (2005): Cardiac series
- Oscar Serafini, Francesco Greco, Gianfranco Misuraca, Mario Chiatto, Antonino Buffon, Echocardiography in the diagnostic and prognostic evaluation of thromboembolic pulmonary hypertension , Monaldi Archives for Chest Disease: Vol. 64 No. 2 (2005): Cardiac series
<< < 30 31 32 33 34 35 36 37 38 39 > >>
You may also start an advanced similarity search for this article.
